RESEARCH ASSOCIATE II - TYPE 1 DIABETES RESEARCH - 10031674

Duarte, CA

City of Hope is an independent biomedical research and treatment center for cancer, diabetes and other life-threatening diseases.

Founded in 1913, City of Hope is a leader in bone marrow transplantation and immunotherapy such as CAR T cell therapy. City of Hope’s translational research and personalized treatment protocols advance care throughout the world. Human synthetic insulin, monoclonal antibodies and numerous breakthrough cancer drugs are based on technology developed at the institution. AccessHope™, a wholly owned subsidiary, was launched in 2019 and is dedicated to serving employers and their health care partners by providing access to City of Hope’s exceptional cancer expertise.

A National Cancer Institute-designated comprehensive cancer center and a founding member of the National Comprehensive Cancer Network, City of Hope is ranked among the nation’s “Best Hospitals” in cancer by U.S. News & World Report and received Magnet Recognition from the American Nurses Credentialing Center. Its main campus is located near Los Angeles, with additional locations throughout Southern California and in Arizona.

Pay Rate: $33.0 - $51.15 per hour

Join the forefront of groundbreaking research at the Beckman Research Institute of City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research.

A Research Associate II position is available in the laboratory of Dr. Melanie Shapiro, PhD, in the AR-DMRI Department of Diabetes Immunology. You will perform a variety of experiments related to the genetics and immunology of type 1 diabetes.

The Shapiro laboratory currently studies germline genetic variants predicting response to immunotherapies for type 1 diabetes as well as somatic variants in the pancreas and immune cells of organ donors with type 1 diabetes.

For more information on the Shapiro Laboratory please visit here: https://mshapirolab.academicwebsite.com/

For more information on the Arthur Riggs Diabetes & Metabolism Research Institute please visit here: https://www.cityofhope.org/research/riggs-institute/diabetes-milestones-and-history

As a successful candidate, you will:

· Isolate and culture immune cells In vitro

· Perform CRISPR/Cas9-mediated gene editing

· Run multicolor flow cytometry and analysis

· Execute ELISA and/or multiplex cytokine quantification assays

· Analyze single nucleotide polymorphism genotyping data

· Perform murine injections, dissection, and processing of pancreas and immune organs for in vivo experiments

· Process and analyze single cell RNA sequencing data

Your qualifications should include:

· Bachelor’s degree. Masters degree preferred

· 2 years of related research/laboratory experience with a Bachelor’s degree or 1 year related research/laboratory experience with a Master’s degree.

· Some experience in the experimental and analytical techniques listed above is preferred, but not required

City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location.

City of Hope is an equal opportunity employer.

To learn more about our Comprehensive Benefits, please CLICK HERE.