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RESEARCH ASSOCIATE II - INTEGRATIVE GENOMICS CORE - 10035003

Duarte, CA

City of Hope is an independent biomedical research and treatment center for cancer, diabetes and other life-threatening diseases. 

Founded in 1913, City of Hope is a leader in bone marrow transplantation and immunotherapy such as CAR T cell therapy. City of Hope’s translational research and personalized treatment protocols advance care throughout the world. Human synthetic insulin, monoclonal antibodies and numerous breakthrough cancer drugs are based on technology developed at the institution. AccessHope™, a wholly owned subsidiary, was launched in 2019 and is dedicated to serving employers and their health care partners by providing access to City of Hope’s exceptional cancer expertise. 

A National Cancer Institute-designated comprehensive cancer center and a founding member of the National Comprehensive Cancer Network, City of Hope is ranked among the nation’s “Best Hospitals” in cancer by U.S. News & World Report and received Magnet Recognition from the American Nurses Credentialing Center. Its main campus is located near Los Angeles, with additional locations throughout Southern California and in Arizona.


Pay Rate: $33.99 - $52.69 per hour

Join the forefront of groundbreaking research at the Beckman Research Institute of City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research.

We are seeking a highly motivated Research Assistant II to join the Integrative Genomics Core. You will support a wide range of genomics workflows, including next-generation sequencing (NGS) library preparation, nucleic acid extraction, and quality control processes.

The Integrative Genomics Core provides comprehensive genomics services to support cutting-edge biomedical research. Leveraging advanced platforms such as Illumina, PacBio, Nanopore, and 10x Genomics, the core enables a broad range of genomic and epigenomic applications. These technologies empower investigators to explore complex biological systems, from cancer genomics to translational and precision medicine studies, within a highly collaborative, service-oriented environment.

As a successful candidate, you will:

  • Perform DNA and RNA extraction, quantification, and quality control
  • Prepare libraries for next-generation sequencing using Illumina, PacBio (SMRT sequencing), and 10x Genomics platforms
  • Execute high-throughput workflows with attention to consistency and quality
  • Track samples and metadata using laboratory information management systems FileMaker
  • Maintain accurate and detailed laboratory records in accordance with core facility standards
  • Assist in method development, optimization, and validation of new genomics workflows under supervision of core scientists
  • Communicate effectively with core scientists regarding sample requirements, project status, and results

Your qualifications should include:

  • Bachelor’s degree in molecular biology, Genetics, or related field. Master’s degree preferred.
  • 2 years of related experience in molecular biology or genomics with a Bachelor’s degree or 1 year related experience with a Master’s degree.
  • Experience with standard molecular biology techniques (PCR, qPCR, nucleic acid handling)
  • 2 years of Direct experience with next-generation sequencing library preparation is preferred
  • Familiarity with Illumina sequencing platforms.
  • Experience with long-read sequencing (PacBio) and/or single-cell or spatial genomics workflows (10x Genomics)

City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location.

City of Hope is an equal opportunity employer.

To learn more about our Comprehensive Benefits, please CLICK HERE.

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