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RESEARCH ASSOCIATE I - PRECISION ONCOLOGY OF GASTROINTESTINAL CANCERS - 10026948

Monrovia, CA

City of Hope is an independent biomedical research and treatment center for cancer, diabetes and other life-threatening diseases. 

Founded in 1913, City of Hope is a leader in bone marrow transplantation and immunotherapy such as CAR T cell therapy. City of Hope’s translational research and personalized treatment protocols advance care throughout the world. Human synthetic insulin, monoclonal antibodies and numerous breakthrough cancer drugs are based on technology developed at the institution. AccessHope™, a wholly owned subsidiary, was launched in 2019 and is dedicated to serving employers and their health care partners by providing access to City of Hope’s exceptional cancer expertise. 

A National Cancer Institute-designated comprehensive cancer center and a founding member of the National Comprehensive Cancer Network, City of Hope is ranked among the nation’s “Best Hospitals” in cancer by U.S. News & World Report and received Magnet Recognition from the American Nurses Credentialing Center. Its main campus is located near Los Angeles, with additional locations throughout Southern California and in Arizona.


Pay Rate: $25.13 - $29.15 per hour

Join the transformative team at City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes,

and other life-threatening illnesses. City of Hope’s growing national system includes its Los Angeles campus, a network of clinical care locations across Southern California, a new cancer center in Orange County, California, and treatment facilities in Atlanta, Chicago and Phoenix. our dedicated and compassionate employees are driven by a common mission: To deliver the cures of tomorrow to the people who need them today. 

We seek a Research Associate candidate within the multidisciplinary research team headed by Dr. Ajay Goel, Professor and Chair Department of Molecular Diagnostics and Experimental Therapeutics and Associate Director of Basic Sciences, City of Hope Comprehensive Cancer. Our research is focused on translational research on the genomic and epigenomic characterization of various gastrointestinal cancers (GI), including colorectal, pancreatic, and gastric cancers. 

Some of the key research topics in our laboratory include:

  1. Developing ctDNA and cfRNA-based liquid biopsy biomarkers for cancer diagnosis, prognosis, and predictive responses to various therapies. 
  2. Study the epigenetic basis of GI cancers (e.g., aberrant DNA methylation, histone modifications, and non-coding RNAs).
  3. The genetic basis of early-onset and familial/hereditary colorectal cancers. 
  4. The role of the tumor microenvironment, stem cells, immune regulation, and identification of novel targeted therapies. 
  5. The role of extracellular vesicles/exosomes in cancer pathogenesis and their role as disease biomarkers. 

As a successful candidate, you will:

  • Maintain various aspects of lab management, including maintenance and upkeep of reagent and clinical specimen inventories, ordering, lab safety, and regulatory tasks.
  • Ensure that all laboratory activities comply with each procedure(s) by utilizing safety procedures and guidelines in handling, storage, and disposal of bio-hazardous, infectious, and toxic material.
  • Perform a variety of routine and non-routine laboratory research experiments nd record and validate results for accuracy and completeness.
  • Perform Cancer Genetics and Epigenetics techniques and general lab maintenance that assists in conducting an Investigator’s Research Project. 
  • Be responsible for accurately recording work performed, including results and methodology. 

Your qualifications should include:

  • Bachelor’s or master’s degree; master’s degree preferred.
  • Two years of laboratory experience with a bachelor’s degree or 3 years of related research/ laboratory experience with a master’s degree
  • Assist and perform various molecular biology techniques, such as tissue culture, flow cytometry (analysis), and molecular tests, according to the Laboratory’s Standard Operating Procedures.

City of Hope is an equal opportunity employer.  To learn more about our commitment to diversity, equity, and inclusion, please click here.

To learn more about our Comprehensive Benefits, please CLICK HERE.

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