Jobs filters
CLINICAL PRACTICE EDUCATION SPECIALIST (CPES) - 10027637
Irvine, CARESEARCH ASSOCIATE I - PRECISION ONCOLOGY OF GASTROINTESTINAL CANCERS - 10026948
Monrovia, CASENIOR PHYSICIAN RECRUITER (REMOTE WITH TRAVEL REQUIRED) - 10027429
Duarte, CAMOLECULAR CLINICAL VARIANT CURATOR - 10027352
Irwindale, CANURSE MANAGER - INFUSION CLINIC - 10027643
Duarte, CACLINICAL RESEARCH ASSOCIATE I - MICROBIOME PROGRAM - 10025241
Duarte, CASTAFF SCIENTIST/COMPUTATIONAL BIOLOGIST - 10026115
Duarte, CACLINICAL FACULTY | INTERVENTIONAL PULMONARY AND CRITICAL CARE MEDICINE | DUARTE, CA - 10027448
Duarte, CADPS CLINICAL RESEARCH ASSISTANT I - 10027362
Duarte, CAPAYMENT POSTER - 10027065
Irwindale, CAPHYSICAL THERAPIST I - 10027319
Duarte, CARESEARCH ASSOCIATE II - CANCER IMMUNOLOGY - 10027460
Duarte, CA
MOLECULAR CLINICAL VARIANT CURATOR - 10027352
Irwindale, CACity of Hope is an independent biomedical research and treatment center for cancer, diabetes and other life-threatening diseases.
Founded in 1913, City of Hope is a leader in bone marrow transplantation and immunotherapy such as CAR T cell therapy. City of Hope’s translational research and personalized treatment protocols advance care throughout the world. Human synthetic insulin, monoclonal antibodies and numerous breakthrough cancer drugs are based on technology developed at the institution. AccessHope™, a wholly owned subsidiary, was launched in 2019 and is dedicated to serving employers and their health care partners by providing access to City of Hope’s exceptional cancer expertise.
A National Cancer Institute-designated comprehensive cancer center and a founding member of the National Comprehensive Cancer Network, City of Hope is ranked among the nation’s “Best Hospitals” in cancer by U.S. News & World Report and received Magnet Recognition from the American Nurses Credentialing Center. Its main campus is located near Los Angeles, with additional locations throughout Southern California and in Arizona.
Molecular Clinical Variant Curator - Clinical Molecular Diagnostic Laboratory
Join the transformative team at City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. City of Hope’s growing national system includes its Los Angeles campus, a network of clinical care locations across Southern California, a new cancer center in Orange County, California, and treatment facilities in Atlanta, Chicago and Phoenix. Our dedicated and compassionate employees are driven by a common mission: To deliver the cures of tomorrow to the people who need them today.
This full-time position reports directly to the Director of the Clinical Molecular Diagnostic Laboratory (CMDL). The Clinical Variant Curator plays a crucial role in supporting both clinical and developmental operations of the CMDL. Responsibilities include accurately identifying and classifying genetic variants/mutations detected through standard molecular genetic testing. The curator will also assist clinical laboratory leadership in ongoing test development and optimization of clinical testing pipelines, contributing to the interpretation and classification of genetic variants. This is a Monday-Friday, full-time, days position.
As a successful candidate, you will:
- Curate and classify genetic variants/mutations using databases, literature, and in-silico tools, ensuring accurate clinical reporting.
- Collaborate with department leadership to validate and implement new methods and instrumentation.
- Troubleshoot and resolve complex technical issues, providing guidance to staff as needed.
- Participate in professional development and training to maintain high standards of laboratory care.
- Ensure compliance with departmental policies, procedures, and regulatory requirements.
- Assist in updating CMDL mutation databases and incorporating new algorithms into clinical analysis pipelines.
Your qualifications should include:
- Master’s Degree in Biological Sciences and familiarity with Germline databases, Sanger Sequencing and Next-generation sequencing (NGS) or Bachelor’s Degree and familiarity with Germline databases, Sanger Sequencing and Next-generation sequencing (NGS) and 2 years of sequencing data interpretation.
- Knowledge of principles and practices of computational biology as applied to genetics/genomics.
- An understanding of bioinformatics analysis to identify variants within genomic data sets, and variant effect prediction algorithms.
- Laboratory and/or clinical experience in cancer genetics.
- The ability to critically read, understand, and interpret data from scientific publications. Cross-disciplinary and strong analytical skills as well as broad experience using computational methods, databases, software and hardware.
City of Hope is an equal opportunity employer. To learn more about our commitment to diversity, equity, and inclusion, please click here.
To learn more about our Comprehensive Benefits, please CLICK HERE.