STAFF SCIENTIST - IMMUNOTHERAPY AND CAR T CELL ENGINEERING - 10032267

Duarte, CA

City of Hope is an independent biomedical research and treatment center for cancer, diabetes and other life-threatening diseases.

Founded in 1913, City of Hope is a leader in bone marrow transplantation and immunotherapy such as CAR T cell therapy. City of Hope’s translational research and personalized treatment protocols advance care throughout the world. Human synthetic insulin, monoclonal antibodies and numerous breakthrough cancer drugs are based on technology developed at the institution. AccessHope™, a wholly owned subsidiary, was launched in 2019 and is dedicated to serving employers and their health care partners by providing access to City of Hope’s exceptional cancer expertise.

A National Cancer Institute-designated comprehensive cancer center and a founding member of the National Comprehensive Cancer Network, City of Hope is ranked among the nation’s “Best Hospitals” in cancer by U.S. News & World Report and received Magnet Recognition from the American Nurses Credentialing Center. Its main campus is located near Los Angeles, with additional locations throughout Southern California and in Arizona.

Pay Rate: $38.67 - $127.69 per hour

Join the Pediatric Immunotherapy Research Lab (PI: Leo Wang) in the Beckman Research Institute of City of Hope, where we use cutting-edge techniques to understand and engineer potent immune responses against pediatric cancers.

We are currently looking for a bright, ambitious, creative, and kind Staff Scientist with expertise and interest in fundamental immunology to join our group. We couple protein-focused molecular techniques with in vitro and in vivo disease models, as well as groundbreaking clinical trials, to understand how chimeric antigen receptors (CARs) signal and communicate with the endogenous immune system. We use this information to design solid-tumor targeted CAR effector cells with improved persistence and potency, as well as the ability to amplify the antitumor immune response.

As a successful candidate, you will:

Design and lead projects focused on understanding and augmenting CAR T cell function in specific microenvironmental contexts, using canonical immune signaling and activation as a conceptual framework.
Coordinate lab tasks and operations among multiple lab members, including mentoring, training, and oversight; providing conceptual, technical, and experimental assistance; contributing to manuscripts and grant applications; and assembling reports and presentations.
Keep detailed and accurate logs of experimental design and primary data, analysis, and synthesis.
Prepare data presentations and manuscripts for publication.
Organize and maintain project workflow, both internally and in collaborations with other labs.

Your qualifications should include:

The Staff Scientist must possess, at a minimum, a Ph.D. or other doctoral level degree, or equivalent professional experience.
Core competencies include cell and molecular biology, flow cytometry, protein biochemistry, and mouse work.
Extensive prior experience in immunology or a closely related field.

Preferred qualifications:

· Ph.D. or equivalent degree and 5 or more years of postdoctoral experience. Programming experience (R, Python).

City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location.

City of Hope is an equal opportunity employer.

To learn more about our Comprehensive Benefits, pleaseCLICK HERE.

STAFF SCIENTIST - IMMUNOTHERAPY AND CAR T CELL ENGINEERING - 10032267

Duarte, CA

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City of Hope is an independent biomedical research and treatment center for cancer, diabetes and other life-threatening diseases.

Pay Rate: $38.67 - $127.69 per hour

As a successful candidate, you will:

Design and lead projects focused on understanding and augmenting CAR T cell function in specific microenvironmental contexts, using canonical immune signaling and activation as a conceptual framework.
Coordinate lab tasks and operations among multiple lab members, including mentoring, training, and oversight; providing conceptual, technical, and experimental assistance; contributing to manuscripts and grant applications; and assembling reports and presentations.
Keep detailed and accurate logs of experimental design and primary data, analysis, and synthesis.
Prepare data presentations and manuscripts for publication.
Organize and maintain project workflow, both internally and in collaborations with other labs.

Your qualifications should include:

The Staff Scientist must possess, at a minimum, a Ph.D. or other doctoral level degree, or equivalent professional experience.
Core competencies include cell and molecular biology, flow cytometry, protein biochemistry, and mouse work.
Extensive prior experience in immunology or a closely related field.

Preferred qualifications:

· Ph.D. or equivalent degree and 5 or more years of postdoctoral experience. Programming experience (R, Python).

City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location.

City of Hope is an equal opportunity employer.

To learn more about our Comprehensive Benefits, pleaseCLICK HERE.

Pay Rate: $38.67 - $127.69 per hour

As a successful candidate, you will:

Design and lead projects focused on understanding and augmenting CAR T cell function in specific microenvironmental contexts, using canonical immune signaling and activation as a conceptual framework.
Coordinate lab tasks and operations among multiple lab members, including mentoring, training, and oversight; providing conceptual, technical, and experimental assistance; contributing to manuscripts and grant applications; and assembling reports and presentations.
Keep detailed and accurate logs of experimental design and primary data, analysis, and synthesis.
Prepare data presentations and manuscripts for publication.
Organize and maintain project workflow, both internally and in collaborations with other labs.

Your qualifications should include:

The Staff Scientist must possess, at a minimum, a Ph.D. or other doctoral level degree, or equivalent professional experience.
Core competencies include cell and molecular biology, flow cytometry, protein biochemistry, and mouse work.
Extensive prior experience in immunology or a closely related field.

Preferred qualifications:

· Ph.D. or equivalent degree and 5 or more years of postdoctoral experience. Programming experience (R, Python).

City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location.

City of Hope is an equal opportunity employer.

To learn more about our Comprehensive Benefits, pleaseCLICK HERE.

PHYSICIAN | GYNECOLOGIC MEDICAL ONCOLOGIST | COHNMC LOS ANGELES, CA - 10032305