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Irvine, CA
POSTDOCTORAL FELLOW - LEUKEMIA AND SOLID TUMOR THERAPEUTICS - 10032299
Duarte, CACity of Hope is an independent biomedical research and treatment center for cancer, diabetes and other life-threatening diseases.
Founded in 1913, City of Hope is a leader in bone marrow transplantation and immunotherapy such as CAR T cell therapy. City of Hope’s translational research and personalized treatment protocols advance care throughout the world. Human synthetic insulin, monoclonal antibodies and numerous breakthrough cancer drugs are based on technology developed at the institution. AccessHope™, a wholly owned subsidiary, was launched in 2019 and is dedicated to serving employers and their health care partners by providing access to City of Hope’s exceptional cancer expertise.
A National Cancer Institute-designated comprehensive cancer center and a founding member of the National Comprehensive Cancer Network, City of Hope is ranked among the nation’s “Best Hospitals” in cancer by U.S. News & World Report and received Magnet Recognition from the American Nurses Credentialing Center. Its main campus is located near Los Angeles, with additional locations throughout Southern California and in Arizona.
Join the forefront of groundbreaking research at City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research.
The laboratories of Dr. Le Xuan Truong Nguyen in the Department of Hematological Malignancies and Translational Sciences are seeking highly motivated and innovative Postdoctoral Fellow. This is an excellent opportunity to join a well-established team and lead projects that culminate in publications in high-impact journals.
Our research focuses on drug development, uncovering basic mechanisms, and identifying novel therapeutic targets in leukemogenesis and solid tumors. Specifically, we study genetic and epigenetic biomarkers with prognostic value in acute myeloid leukemia (AML) and other solid cancers. Our work emphasizes therapeutic candidates targeting mitochondrial vulnerabilities, including nucleoside analogs, small GTPase inhibitors, natural plant extracts, and immunotherapies.
As a successful candidate you will:
· Performing experimental procedures
· Manage data, analyze, and report findings
· Write scientific papers
· Work with PI and other team members to perform experiments in vitro and in vivo
· Utilize the following in vitro skills (not limited to but including):
o Aseptic techniques, cell culture, western blot, RNA/DNA extraction, protein extraction, RT-qPCR, seahorse, northern blot, bacterial transformation, cloning, lentivirus production, etc.
· Utilize the following in vivo skills (not limited to but including):
o Basic routes of administration (oral gavage, intraperitoneal, retro-orbital, subcutaneous, intra-venous injections), blood collection, organ harvesting (spleen, bone marrow, liver, etc.)
Your qualifications should include:
· A Ph.D. degree in life or biomedical sciences, or related discipline is required.
· Preferred experience in molecular signaling, cancer biology, leukemia research, and extensive murine studies.
· Experience in immunology is an advantage.
City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location.
City of Hope is an equal opportunity employer.
To learn more about our Comprehensive Benefits, pleaseCLICK HERE.
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