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VP, TRANSLATIONAL PORTFOLIO AND NEW VENTURES - 10036062

Remote, US

City of Hope is an independent biomedical research and treatment center for cancer, diabetes and other life-threatening diseases. 

Founded in 1913, City of Hope is a leader in bone marrow transplantation and immunotherapy such as CAR T cell therapy. City of Hope’s translational research and personalized treatment protocols advance care throughout the world. Human synthetic insulin, monoclonal antibodies and numerous breakthrough cancer drugs are based on technology developed at the institution. AccessHope™, a wholly owned subsidiary, was launched in 2019 and is dedicated to serving employers and their health care partners by providing access to City of Hope’s exceptional cancer expertise. 

A National Cancer Institute-designated comprehensive cancer center and a founding member of the National Comprehensive Cancer Network, City of Hope is ranked among the nation’s “Best Hospitals” in cancer by U.S. News & World Report and received Magnet Recognition from the American Nurses Credentialing Center. Its main campus is located near Los Angeles, with additional locations throughout Southern California and in Arizona.


Pay Rate: $116.99 - $210.58 per hour

Join the transformative team at City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. City of Hope’s growing national system includes its Los Angeles campus, a network of clinical care locations across Southern California, a new cancer center in Orange County, California, and treatment facilities in Atlanta, Chicago and Phoenix. Our dedicated and compassionate employees are driven by a common mission: To deliver the cures of tomorrow to the people who need them today.

City of Hope is undergoing a transformative evolution of its commercialization and strategic partnerships organization to accelerate the translation of scientific innovation into impactful solutions for patients. As we build a more integrated and externally facing commercial engine, we are expanding capabilities across business development, venture creation, strategic partnerships, translational acceleration, and innovation ecosystem development. This is a unique opportunity to join and help shape a next-generation commercialization organization designed to strengthen industry collaboration, advance breakthrough therapies and technologies, and maximize the impact of City of Hope’s world-class research enterprise.

As Vice President, Translational Portfolio & New Ventures, you will translate the strategic priorities of Hope Catalyst into a rigorous portfolio and operating model. You will establish execution plans, governance processes, milestones, decision points, resource requirements, and performance metrics for accelerator-supported programs while ensuring projects progress efficiently toward key value-inflection points. This highly visible leadership role provides end-to-end oversight of portfolio operations, from project intake and prioritization through translational development, external partnering, licensing, and new company formation.

As a successful candidate, you will:

  • Lead the Hope Catalyst translational portfolio, overseeing programs from selection through commercialization, licensing, strategic partnerships, or company creation.
  • Establish portfolio governance and stage-gate processes, including prioritization criteria, milestones, decision points, and advancement requirements.
  • Develop and oversee integrated execution plans spanning scientific, clinical, regulatory, intellectual property, commercial, operational, and financial objectives.
  • Drive execution excellence by proactively identifying risks, removing barriers, and ensuring programs remain on track to achieve critical milestones.
  • Manage portfolio performance through executive reporting, KPI dashboards, budget oversight, resource allocation, and timeline management.
  • Lead investment and prioritization decisions, recommending which programs should be accelerated, partnered, licensed, redirected, paused, or discontinued.
  • Partner with investigators and scientific leaders to translate groundbreaking discoveries into viable product strategies and commercialization pathways.
  • Lead new venture creation efforts, including company strategy, financing plans, investor engagement, and identification of leadership teams.
  • Coordinate internal and external stakeholders across licensing, regulatory, legal, finance, clinical development, manufacturing, and business development functions.
  • Build and expand relationships with investors, entrepreneurs, industry partners, and advisors to advance funding opportunities, partnerships, company creation, and patient impact.

Your qualifications should include:

  • PhD with 15 years of relevant industry experience plus an MBA preferred; or a Master’s degree with an MBA and 20 years of relevant industry experience.
  • Demonstrated leadership experience within the pharmaceutical, biotechnology, healthcare, or life sciences industries.
  • Proven success advancing biomedical innovations from discovery through development, partnering, licensing, or company formation.
  • Deep understanding of translational science, drug development, regulatory strategy, intellectual property, and asset de-risking.
  • Experience evaluating scientific programs for commercial potential, market opportunity, competitive differentiation, and investment readiness.
  • Track record of collaborating with academic investigators, clinicians, entrepreneurs, investors, industry partners, and cross-functional stakeholders.
  • Experience developing milestone-driven plans, managing go/no-go decisions, and prioritizing investments based on objective criteria.
  • Exceptional executive presence, communication skills, strategic judgment, and leadership capabilities within complex organizations.
  • Experience in venture creation, venture capital, accelerator programs, biotech business development, or company formation strongly preferred.
  • Established network within venture capital, biotechnology, pharmaceutical, and innovation ecosystems preferred.

At City of Hope, you'll have the opportunity to help shape how breakthrough discoveries become therapies, technologies, and companies that improve and save lives around the world. If you're a visionary commercialization leader with a passion for translating innovation into patient impact, we encourage you to apply today.

City of Hope employees’ pay is based on the following criteria: work experience, qualifications, and work location.

City of Hope is an equal opportunity employer.

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