Jobs filters
POSTDOCTORAL FELLOW - DIABETES AND CANCER METABOLISM RESEARCH - 10028329
Duarte, CACity of Hope is an independent biomedical research and treatment center for cancer, diabetes and other life-threatening diseases.
Founded in 1913, City of Hope is a leader in bone marrow transplantation and immunotherapy such as CAR T cell therapy. City of Hope’s translational research and personalized treatment protocols advance care throughout the world. Human synthetic insulin, monoclonal antibodies and numerous breakthrough cancer drugs are based on technology developed at the institution. AccessHope™, a wholly owned subsidiary, was launched in 2019 and is dedicated to serving employers and their health care partners by providing access to City of Hope’s exceptional cancer expertise.
A National Cancer Institute-designated comprehensive cancer center and a founding member of the National Comprehensive Cancer Network, City of Hope is ranked among the nation’s “Best Hospitals” in cancer by U.S. News & World Report and received Magnet Recognition from the American Nurses Credentialing Center. Its main campus is located near Los Angeles, with additional locations throughout Southern California and in Arizona.
Join the forefront of groundbreaking research at the Beckman Research Institute of City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research.
A postdoctoral position is open in the laboratory of Yingfeng Deng in the Department of Diabetes and Cancer Metabolism at the City of Hope Beckman Research Institute. The Deng laboratory studies the homeostasis of uridine and its role in metabolism, which provides a new angle for understanding the pathophysiology of obesity, diabetes and cancer.
Work in the lab utilizes both genetically engineered mouse models and in vitro systems. A combination of state-of-the-art surgical, genetic, cellular, biochemical, imaging, and metabolic flux approaches is currently used in the lab. Following up with the new paradigm revealed about uridine metabolism by Drs. Deng and Scherer (Science, 2017), the Deng lab is currently focusing on three areas: 1) the role of uridine in the progression of obesity and diabetes. 2) the physiology of uridine in bile and nutrient absorption. 3) the regulation of uridine homeostasis by ER stress and its relevance to breast cancer.
We seek an independent and highly motivated candidate interested in studying the molecular, cellular, and metabolic mechanisms leading to obesity, diabetes, and cancer. Expertise in using mouse models to study metabolic diseases is preferred.
For a complete list of Publications please visit here:https://www.ncbi.nlm.nih.gov/myncbi/1J54E41I5YVku/bibliography/public/
Your qualifications should include:
· Ph.D. and/or M.D. degree in life or biomedical sciences or a related discipline is required.
· Experience in basic molecular biology skills.
· Experience in animal models and lipid metabolism.
· Experience in metabolomics and liver physiology.
· To Apply, please attach a cover letter describing your past training and research interests, a detailed CV and contact information of three referees
City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location.
City of Hope is an equal opportunity employer.
To learn more about our Comprehensive Benefits, please CLICK HERE.