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ASSOCIATE VICE PRESIDENT, REGIONAL PHILANTHROPY - 10035760

Irvine, CA

City of Hope is an independent biomedical research and treatment center for cancer, diabetes and other life-threatening diseases. 

Founded in 1913, City of Hope is a leader in bone marrow transplantation and immunotherapy such as CAR T cell therapy. City of Hope’s translational research and personalized treatment protocols advance care throughout the world. Human synthetic insulin, monoclonal antibodies and numerous breakthrough cancer drugs are based on technology developed at the institution. AccessHope™, a wholly owned subsidiary, was launched in 2019 and is dedicated to serving employers and their health care partners by providing access to City of Hope’s exceptional cancer expertise. 

A National Cancer Institute-designated comprehensive cancer center and a founding member of the National Comprehensive Cancer Network, City of Hope is ranked among the nation’s “Best Hospitals” in cancer by U.S. News & World Report and received Magnet Recognition from the American Nurses Credentialing Center. Its main campus is located near Los Angeles, with additional locations throughout Southern California and in Arizona.


Pay Rate: $84.76 - $141.54 per hour

Join the transformative team at City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. City of Hope’s growing national system includes its Los Angeles campus, a network of clinical care locations across Southern California, a new cancer center in Orange County, California, and treatment facilities in Atlanta, Chicago and Phoenix. Our dedicated and compassionate employees are driven by a common mission: To deliver the cures of tomorrow to the people who need them today.

Focused on eliminating cancer, diabetes and other life-threatening illnesses, City of Hope has established itself as a world-class leader in transforming the future of health. The Office of Philanthropy plays a critical role in advancing this mission by securing the philanthropic resources that fuel groundbreaking research, exceptional patient care, and innovative education programs. As the Associate Vice President, Regional Philanthropy, you will manage a portfolio of some of City of Hope’s most significant donors and prospects, develop sophisticated fundraising strategies, and lead high-performing fundraising teams focused on the Orange County market. This executive-level role serves as both a strategic fundraiser and trusted relationship builder, partnering closely with philanthropy leadership, faculty, administration, and donors to drive transformational philanthropic investments.

As a successful candidate, you will:

  • Manage and grow a portfolio of high-capacity donors and prospects capable of making major and principal gifts.
  • Develop and execute customized cultivation, solicitation, stewardship, and relationship management strategies.
  • Lead complex, multi-year fundraising initiatives that align donor interests with institutional priorities.
  • Build and maintain strong relationships with donors, volunteers, faculty, executives, and community leaders.
  • Supervise, mentor, and develop frontline fundraising professionals and support staff.
  • Partner across City of Hope to support enterprise fundraising goals and strategic priorities.
  • Create and deliver compelling proposals, stewardship reports, gift agreements, donor communications, and executive briefing materials.
  • Utilize fundraising data and analytics to drive prospect strategies, pipeline growth, and achievement of revenue goals.
  • Participate in philanthropy strategy reviews and collaborative planning efforts to enhance donor engagement and outcomes.
  • Represent City of Hope with professionalism, integrity, and a commitment to exceptional donor experiences.

Your qualifications should include:

  • Bachelor's degree in a relevant field required.
  • Advanced degree preferred.
  • 10 years of experience leading development functions with significant emphasis on major and principal gifts.
  • 5 years of experience managing and developing high-performing teams.
  • Demonstrated success securing major philanthropic investments and leading complex donor engagement strategies.
  • Proven experience crafting complex gift agreements and managing negotiations.
  • Strong leadership, coaching, and talent development skills.
  • Exceptional written and verbal communication abilities.
  • Ability to collaborate effectively with faculty, executives, volunteers, and donors.
  • Strong judgment, discretion, and experience handling confidential donor information.
  • Deep understanding of fundraising principles, donor relations, and philanthropic communities.
  • Experience with fundraising and business applications such as Salesforce, Tableau, Microsoft Office Suite, and related systems.

City of Hope employees’ pay is based on the following criteria: work experience, qualifications, and work location.

City of Hope is an equal opportunity employer.

To learn more about our Comprehensive Benefits, pleaseCLICK HERE.

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