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ASSISTANT RESEARCH PROFESSOR - 10032776
Duarte, CACity of Hope is an independent biomedical research and treatment center for cancer, diabetes and other life-threatening diseases.
Founded in 1913, City of Hope is a leader in bone marrow transplantation and immunotherapy such as CAR T cell therapy. City of Hope’s translational research and personalized treatment protocols advance care throughout the world. Human synthetic insulin, monoclonal antibodies and numerous breakthrough cancer drugs are based on technology developed at the institution. AccessHope™, a wholly owned subsidiary, was launched in 2019 and is dedicated to serving employers and their health care partners by providing access to City of Hope’s exceptional cancer expertise.
A National Cancer Institute-designated comprehensive cancer center and a founding member of the National Comprehensive Cancer Network, City of Hope is ranked among the nation’s “Best Hospitals” in cancer by U.S. News & World Report and received Magnet Recognition from the American Nurses Credentialing Center. Its main campus is located near Los Angeles, with additional locations throughout Southern California and in Arizona.
Join the forefront of groundbreaking research at the Beckman Research Institute of City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research.
As a successful candidate you will:
· Design optimized genome editing and gene augmentation vectors for the treatment of genetic diseases, including hypertrophic cardiomyopathy (HCM).
· Design vectors to correct specific pathogenic mutations in target genes in in vivo disease models.
· Create vectors for the targeted insertion of reporters and correction of mutations at specified genomic locations in target genes across species.
· Develop strategies to codon-optimize correction sequences to achieve desired expression levels and optimize editing efficiency.
· Develop strategies to evaluate the outcome of genetic therapies.
· Oversee and guide the cloning of genetic vectors.
Your qualifications should include:
· PhD, MD, or MD/PhD with a strong background in molecular biology, genome editing, or gene therapy.
· Extensive experience in molecular biology and genomics, designing and optimizing gene editing and gene augmentation vectors for in vivo and in vitro applications.
· Evidence of scientific rigor and excellence as documented by high-impact peer-reviewed publications.
· Prior experience in translational research and preclinical model development.
· Demonstrated ability to mentor research associates and technical staff in a laboratory environment.
· Proven track record of collaborative research and contribution to innovative therapeutic strategies.
City of Hope is an equal opportunity employer.
To learn more about our Comprehensive Benefits, please CLICK HERE.